• Associate Professor of Medical Physiology
Andreea Trache profile photo

Educational Background

  • Ph.D., Physics, Institute of Atomic Physics
  • B.S., Physics, University of Bucharest, Romania

Research Interests

  • Dr. Andreea Trache is associate professor in the Texas A&M Health Science Center at Texas A&M University. Her research focuses on the application of advances in physics/optics to the study of biological phenomena at the cellular level. She is interested in developing technologies with unique capabilities that are broadly applicable across biological problems.

    The research in her laboratory has a multidisciplinary approach, being directed towards studying the cellular responses to mechano-chemical stresses at the level of vascular cells: endothelial and smooth muscle cells. Transmission of force is a classical physical concept applied to live cell dynamics, intracellular protein translocation, and transduction of mechanical signals along intracellular pathways. Her lab is interested in studying the molecular mechanisms responsible for altering the intracellular force balance and the effect of mechanotransduction on the reorganization of distant cell-cell and cell-matrix adhesion sites.

Selected Publications

  • Andreea Trache and G. A. Meininger ‘Total Internal Reflection Fluorescence Microscopy’ in Current Protocols in Microbiology, R. Coico, T. Kowalik, J.M. Quarles, B. Stevenson and R.K. Taylor eds., Wiley & Sons Inc., (submitted 2008)
  • S Na, Andreea Trache, Z. Sun, G.A. Meininger, J.D. Humphrey. "Time-dependent changes in cell stiffness and focal adhesion area in response to cyclic stretch" Annals Biomed. Eng. 36 (2008) 369-380.
  • Andreea Trache and G. A. Meininger ‘Atomic Force Microscopy’ in Current Protocols in Microbiology, R. Coico, T. Kowalik, J.M. Quarles, B. Stevenson and R.K. Taylor eds., Wiley & Sons Inc., 2C (2008) 2.1-17
  • MH. Chowdhury, VA Gant, Andreea Trache, A Baldwin, G. A. Meininger and GL Cote. “The use of surface enhanced Raman spectroscopy (SERS) for the detection of human integrins”, Journal of Biomedical Optics 11, 024004 (2006) (8 pages).
  • DM Hawkins,Andreea Trache, AE Ellis, D Stevenson, A Holzenburg, GA Meininger, and SM Reddy. “Quantification and confocal imaging of fluorescently labeled protein specific molecularly imprinted polymers (HydroMIPs)”, Biomacromolecules vol 7 (2006) pp. 2560-2564.