• Associate Professor, Electrical & Computer Engineering
Xiaoning Qian

Educational Background

  • Ph.D., Yale University

Research Interests

  • ·  Bioinformatics:
         - Analysis and intervention in biological networks;
         - Functional data analysis on genomic and proteomic datasets.

    ·  Biomedical image processing and analysis:
         - Image segmentation and robust boundary finding;
         - Shape-based similarity retrieval in multimedia databases.

Selected Publications

  • Byung-Jun Yoon, Xiaoning Qian, Edward R Dougherty, "Quantifying the objective cost of uncertainty in complex dynamic systems," [Paper] IEEE Transactions on Signal Processing, 61(9): 2256--2266, 2013.
  • Yijie Wang and Xiaoning Qian, "A novel subgradient-based optimization algorithm for blockmodel functional module identification," [Paper] BMC Bioinformatics, 14(Suppl 2):S23, 2013.
  • Shaogang Ren, Bo Zeng, and Xiaoning Qian, "Adaptive bi-level programming for optimal gene knockouts for targeted overproduction under phenotypic constraints," [Paper] BMC Bioinformatics, 14(Suppl 2):S17, 2013.
  • Meng Lu, Jianhua Z. Huang, and Xiaoning Qian, "Supervised logistic principal component analysis for pathway based genome-wide association studies," [Paper]ACM Conference on Bioinformatics, Computational Biology and Biomedicine, 2012.
  • Byung-Jun Yoon, Xiaoning Qian, Sayed Mohammad Ebrahim Sahraeian, "Comparative analysis of biological networks using Markov chains and hidden Markov models," [Paper] IEEE Signal Processing Magazine, Special Issue on Genomic and Proteomic Signal Processing in Biomolecular Pathways, 29(1): 22--34, 2012.
  • Xiaoning Qian and Edward R Dougherty, "Intervention in gene regulatory networks via phenotypically constrained control policies based on long-run behavior," [Paper] IEEE/ACM Transactions on Computational Biology and Bioinformatics, 9(1): 123--136, 2012.
  • Xiaoning Qian, Noushin Ghaffari, Ivan Ivanov and Edward R. Dougherty, "State reduction for network intervention in probabilistic Boolean networks," [Paper]Bioinformatics, 26(24): 3098--3104, 2010.
  • Xiaoning Qian, Ivan Ivanov, Noushin Ghaffari and Edward R. Dougherty, Intervention in gene regulatory networks via greedy control policies based on long-run behavior," [Paper] BMC Systems Biology, 3(61): 16 pages, 2009.
  • Xiaoning Qian and Edward R. Dougherty, "On the long-run sensitivity of probabilistic Boolean networks," [Paper] Journal of Theoretical Biology, 257(4): 560--577, 2009.
  • Xiaoning Qian , Sing-Hoi Sze, Byung-Jun Yoon, "Querying pathways in protein interaction networks based on hidden Markov models," [Paper] Journal of Computational Biology, 16(2):145--157, 2009.