• Professor
  • Department Head
  • Presidential Impact Fellow
  • Holder of the Ray B. Nesbitt Endowed Chair
  • Phone: 979-845-3306
  • FAX: 979-845-6446
  • Email: arulj@tamu.edu
  • Office: 222 CHEN
Arul Jayaraman

Educational Background

  • Ph.D.,University of California, Irvine, 1998
  • M.S., Tufts University, 1994
  • B.S., Birla Institute of Technology & Science, 1987

Research Interests

    • Molecular systems biotechnology, specifically on using integrated experimental and modeling approaches for investigating problems in human health and medicine
    • Systems biology of cytokine signaling in inflammatory diseases
    • Inter-kingdom signaling interactions between bacteria and human cells in GI tract infections
    • Development of microfluidic model systems for combinatorial drug screening and vascular tissue engineering

Awards & Honors

  • Texas A&M Presidential Impact Fellow, 2017
  • Texas Engineering Experiment Station Select Fellow, 2017
  • Holder of the Ray Nesbitt Chair, 2016
  • Fellow, American Institute of Medical and Biological Engineering (AIMBE), 2015
  • Engineering Genesis Award, Texas A&M Engineering Experiment Station, 2015
  • Association of Former Students Distinguished Achievement Award in Teaching, 2014
  • Outstanding Service Award, Department of Chemical Engineering, 2014
  • Tenneco Meritorious Teaching Award, 2013
  • Celanese Teaching Excellence Award, 2011
  • TEES Select Young Faculty, 2010
  • NSF CAREER award, 2009

Selected Publications

  • Yang J, Chawla R, Rhee KY, Gupta R, Manson MD, Jayaraman A#, Lele P#. Biphasic chemotaxis of E. coli to the microbiota metabolite indole. Proceedings of the National Academy of Sciences. 2020. #: Corresponding authors
  • Lei, M, Menon R, Manteiga S, Alden S, Hunt C, Alaniz RC, Lee K#, Jayaraman A#. Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice. mSystems 2019. #: Corresponding authors
  • DeLuca JAA, Allred KF, Menon R, Riordan R, Weeks B, Jayaraman A, Allred CD. Bispheno-A alters microbiota metabolites derived from aromatic amino acids and worsens activity during colitis. Experimental Biology and Medicine. 2019.
  • Krishnan S, Ding Y, Saedi N, Choi M, Sridharan GV, Sherr, DH, Yarmush ML, Alaniz RC, Jayaraman A#, Lee K#. Gut microbiota-derived tryptophan metabolites modulate inflammatory response in hepatocytes and macrophages. Cell Reports. 2018. #: Joint corresponding authors
  • Sule N, Pasupuleti S, Kohli N, Menon R, Dangott L, Manson MD, Jayaraman A. The norepinephrine metabolite 3,4-dihydroxymandelic acid is produced by the commensal microbiota and promotes chemotaxis and virulence gene expression in enterohemorrhagic Escherichia coli. Infection & Immunity. 2017
  • Pasupuleti S, Sule N, Manson MD, Jayaraman A. Conversion of the norepinephrine to 3,4-dihydroxymandelic acid in Escherichia coli requires the QseBC quorum sensing system and the FeaR transcription factor. Journal of Bacteriology. 2017. 200(1).
  • Sridharan, G. V., Choi, K. O., Klemashevich, C., Wu, C., Prabhakaran, D., Pan, L., Steinmeyeter, S., Mueller, C., Yousofshahi, M., Alaniz, R. C., Lee, K#. and Jayaraman, A#. “Prediction and quantification of bioactive microbiota metabolites in the mouse gut”. Nature Communications. 2014. #: Joint corresponding authors