Research by Kristen Maitland and Brian Applegate featured on cover of 'Biomedical Optics Express'

Biomedical Optics Express cover

COLLEGE STATION, Texas, May 8, 2013 – An advance in noninvasive imaging of epithelial tissue by two researchers in the Department of Biomedical Engineering at Texas A&M University is featured on the cover of the May 1 issue of “Biomedical Optics Express.”

The work by Assistant Professor Kristen Maitland and Associate Professor Brian Applegate focuses on the development of a chromatic confocal microscope that may enable noninvasive detection and diagnosis of epithelial cancer. The device makes use of chromatic aberration of aspheric lenses to longitudinally disperse broad spectrum light in the sample, spectrally encoding depth information without the need for axial scanning, a major obstacle in noninvasive imaging.

“We present the first microstructural images in non-transparent biological tissue with sufficient depth range and axial resolution to resolve cell morphology in the epithelium,” Maitland says.

Maitland joined the Department of Biomedical Engineering in 2008 after completing her undergraduate studies and master’s degree at California Polytechnic State University and earning her Ph.D. at The University of Texas at Austin. She is recipient of the National Science Foundation (NSF) CAREER Award and the Texas A&M Women’s Progress Award as well as a Texas A&M Engineering Experiment Station Select Young Faculty member. 

Applegate joined the Department of Biomedical Engineering in 2006 after completing his undergraduate studies at Wright State University. He earned his master’s degree and Ph.D. at Ohio State University. Prior to joining Texas A&M, Applegate served as a postdoctoral fellow at the University of North Carolina at Chapel Hill and Duke University. He is recipient of the NSF CAREER Award.