Michigan professor to give optical spectroscopy talk Monday

Mary-Ann Mycek, associate professor and associate chair of the University of Michigan's Department of Biomedical Engineering, will give a seminar on optical spectroscopy Monday (March 1) at 4:10 p.m. in Room 104 of the Jack E. Brown Engineering Building at Texas A&M University.Mycek's talk, "Optical Spectroscopy for Clinical Detection of Pancreatic Cancer," is part of the Department of Biomedical Engineering's seminar series.Abstract Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States, with a five‐year survival rate of only 5 percent. The inability of current clinical methods to accurately detect pancreatic cancer in its early stages leads to this dismal prognosis. To investigate whether tissue optical spectroscopy could potentially aid in early diagnosis and improve survival rates, a prototype clinical fluorescence and reflectance spectrometer was developed and employed in a pilot study to probe freshly excised human pancreatic tissues. Significant differences were observed in the optical responses of normal tissues, pancreatitis, and adenocarcinoma. Quantitative tissue‐photon interaction models and tissue classification algorithms were developed and applied to successfully distinguish among these pancreatic tissue types. These studies suggest that multimodal optical spectroscopy holds promise as a clinical method to differentiate among diseased and normal pancreatic tissues.Biography Mary‐Ann Mycek, Ph.D., is an associate professor in the biomedical engineering department at the University of Michigan. She received her Ph.D. in physics from the University of California, Berkeley, where she specialized in condensed matter physics and optical spectroscopy, before pursuing postdoctoral training in laser medicine at Massachusetts General Hospital and Harvard Medical School. As an assistant professor of physics at Dartmouth, she established an experimental and computational research group in biomedical optics, a multidisciplinary field incorporating elements of the physical and life sciences, engineering, and medicine. At the University of Michigan, she joined the College of Engineering as an associate professor of biomedical engineering and established the Biomedical Optics Laser Laboratory. Her translational research program includes basic (pre‐clinical), applied (clinical), and computational research toward quantitative, noninvasive, optical sensing and imaging in cells and tissues. Currently, she also serves as an associate chair for the biomedical engineering department and in this capacity is director of the graduate program.